PT-141
Research-Grade Peptide · 99%+ Purity · COA Certified
Volume Discounts
Product Description
Synthetic Peptide for Melanocortin Receptor Research
Technical Overview
PT-141 10mg is a synthetic peptide compound developed for laboratory research involving melanocortin signaling and central neuroendocrine pathways, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying MC3R and MC4R receptor binding, downstream cAMP signaling in hypothalamic models, and related biochemical mechanisms.
PT-141 (bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH) featuring a side-chain lactam bridge between Asp and Lys, N-terminal acetylation, and incorporation of norleucine and D-phenylalanine for protease resistance. It is a non-selective agonist of MC1R, MC3R, MC4R, and MC5R with preferential activity at MC3R/MC4R.
Researchers use PT-141 to investigate central melanocortin signaling, sexual-behavior circuits in rodent models, and receptor-selectivity comparisons against alpha-MSH and NDP-MSH. Its protease-resistant structure makes it a stable reference compound for melanocortin receptor pharmacology.
This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.
Specifications
Compound Name: PT-141
Strength: 10mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.
Notice
Provided as a reference material for scientific investigation only.
Product Specifications
| CAS Number | 189691-06-3 |
|---|---|
| Molecular Formula | C50H68N14O10 |
| Molecular Weight (g/mol) | 1025.16 |
| Amino Acid Count | 7 |
| Amino Acid Sequence | Cyclic heptapeptide Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH with a side-chain lactam bridge between Asp and Lys; N-terminal acetylation and incorporation of norleucine and D-Phe confer protease resistance (full sequence per COA). |
| Purity | �?�99% by HPLC �� COA available |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations. |
| Storage Conditions | Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol. |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not for human or animal consumption.
Research Workflow Steps
Store Properly
Refrigerate reconstituted solution at 2–8°C. Use within 30 days.
Document Research
Log batch number, concentration, and research notes per lab protocol.
Product Quality Guarantee
We are continuously conducting HPLC testing on all of our raw powders as well as our finished products to ensure the quality of what we ship. You can have the product you bought from us independently tested at any HPLC-licensed testing facility — and if the results come back negative, we will refund the following:
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About This Product
Is this peptide research grade?
Yes. All our peptides are 99%+ purity research grade, verified by independent 3rd-party labs with full Certificates of Analysis.
What does "Research Use Only" mean?
Our peptides are intended exclusively for laboratory research and educational purposes. They are not manufactured for human consumption, diagnostic use, or therapeutic application.
How do I store this product?
Unreconstituted: store at -20°C for long-term storage or room temperature for up to 30 days. Reconstituted: refrigerate at 2-8°C and use within 30 days.
How fast will my order ship?
Orders placed before 2PM EST ship same-day via tracked shipping. Most USA orders arrive within 2-3 business days.
Can I see the COA before buying?
Yes. Every batch COA is available on our COA page before purchase — not after.
What if I'm not satisfied?
We stand behind our quality. If the product doesn't meet specifications, contact us within 7 days of delivery and we'll make it right.
