IGF-1 LR3
Research-Grade Peptide · 99%+ Purity · COA Certified
Volume Discounts
Product Description
Synthetic Peptide for Growth Factor Research
Technical Overview
IGF-1 LR3 1mg is a synthetic peptide compound developed for laboratory research involving insulin-like growth factor signaling and somatomedin pathway analysis, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying IGF-1 receptor activation profiles, PI3K/Akt and MAPK pathway dynamics, and related biochemical mechanisms.
IGF-1 LR3 is a recombinant 83-residue IGF-1 analog with arginine substituted for glutamic acid at position 3 and an additional 13-residue N-terminal extension. These modifications dramatically reduce binding to IGF binding proteins (IGFBP-1 through IGFBP-6), increasing the proportion of bioavailable peptide for receptor interaction in cell-culture systems.
Researchers utilize this analog to study cell-cycle progression, protein synthesis, and survival signaling in myoblast, hepatocyte, and stem-cell models. Its reduced IGFBP affinity makes it a preferred tool for distinguishing receptor-mediated effects from binding-protein-mediated sequestration.
This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.
Specifications
Compound Name: IGF-1 LR3
Strength: 1mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.
Notice
Provided as a reference material for scientific investigation only.
Product Specifications
| CAS Number | 946870-92-4 |
|---|---|
| Molecular Formula | C400H625N111O115S9 |
| Molecular Weight (g/mol) | 9117.60 |
| Amino Acid Count | 83 |
| Amino Acid Sequence | 83-residue recombinant IGF-1 analog with Arg substituted for Glu at position 3 and a 13-residue N-terminal extension; modifications reduce IGFBP affinity and extend circulating half-life relative to native IGF-1 (full sequence per COA). |
| Purity | �?�99% by HPLC �� COA available |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations. |
| Storage Conditions | Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol. |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not for human or animal consumption.
Research Workflow Steps
Store Properly
Refrigerate reconstituted solution at 2–8°C. Use within 30 days.
Document Research
Log batch number, concentration, and research notes per lab protocol.
Product Quality Guarantee
We are continuously conducting HPLC testing on all of our raw powders as well as our finished products to ensure the quality of what we ship. You can have the product you bought from us independently tested at any HPLC-licensed testing facility — and if the results come back negative, we will refund the following:
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About This Product
Is this peptide research grade?
Yes. All our peptides are 99%+ purity research grade, verified by independent 3rd-party labs with full Certificates of Analysis.
What does "Research Use Only" mean?
Our peptides are intended exclusively for laboratory research and educational purposes. They are not manufactured for human consumption, diagnostic use, or therapeutic application.
How do I store this product?
Unreconstituted: store at -20°C for long-term storage or room temperature for up to 30 days. Reconstituted: refrigerate at 2-8°C and use within 30 days.
How fast will my order ship?
Orders placed before 2PM EST ship same-day via tracked shipping. Most USA orders arrive within 2-3 business days.
Can I see the COA before buying?
Yes. Every batch COA is available on our COA page before purchase — not after.
What if I'm not satisfied?
We stand behind our quality. If the product doesn't meet specifications, contact us within 7 days of delivery and we'll make it right.
